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Study: Supplement Improves Mental Health in Pregnancy

Posted on : June 10, 2024 by Hardy Nutritionals® No Comments

New Study: Hardy’s Daily Essential Nutrients Prenatal Improves Mental Health in Pregnancy, Overall Health of Babies

We are thrilled to share some exciting news!

recent study has revealed significant findings about the effectiveness of Hardy Nutritionals' Daily Essential Nutrients in treating symptoms of antenatal depression. This groundbreaking 12-week, fully blinded, randomized, controlled trial known as the NUTRIMUM study, published in the British Journal of Psychiatry, underscores the potential of DEN as a powerful tool for prenatal mental health support.

Key Findings During Pregnancy
The clinical trial involved 88 participants who were diagnosed with mood disorders, including depression, anxiety, and personality difficulties (i.e. difficulty making & keeping friends, impulsivity, inability to trust, short tempers, excess worry, perfectionism). These individuals were divided into two groups: one received Hardy Nutritionals' Daily Essential Nutrients, and the other was given a placebo. Over the course of twelve weeks, researchers closely monitored the participants' mental health and overall well-being.


Improved Overall Functioning

Compared to those in the placebo group, participants who took Hardy Nutritionals' Daily Essential Nutrients (DEN) demonstrated better overall functioning as rated by their doctors.

Enhanced Sleep Quality

The micronutrient group showed significantly greater improvement in the sleep assessment than the placebo group.

Greater Improvement in Depression Scores

Clinicians rated the depression of micronutrient users to be significantly improved over placebo users by the end of the study. Interestingly, participants who had previously tried psychiatric medications experienced a greater change in depression scores in the micronutrient group than in the placebo group. This may suggest that micronutrients are especially necessary and beneficial to those who respond poorly to pharmaceutical antidepressants.

Positive Response to Personality Difficulties

Individuals with personality difficulties such as impulsivity, untrusting behavior, and perfectionism were much more likely to respond positively to the micronutrients.

High Levels of Self-Reported Improvement

A higher percentage of the micronutrient group identified as ‘much’ to ‘very much’ improved (68.8%) compared to the placebo group (38.5%).

Lower Homocysteine

Daily Essential Nutrients increased blood levels of vitamins D and B12 and lowered homocysteine significantly, reducing the risk for multiple pregnancy complications. High homocysteine has been associated with neural tube defects, recurrent miscarriage, preeclampsia, preterm delivery, partial placenta detachment, fetal growth restriction, and gestational diabetes.

Viable Option During Pregnancy 

Most women are especially careful about what they take into their bodies while they are carrying a growing baby. This study provides high-quality medical evidence that Hardy Nutritionals' Daily Essential Nutrients is an excellent option for pregnant women seeking natural, side effect-free, and effective support for their mental health. See the study.

Key Findings for the Babies
In addition to evaluating the benefits of DEN in mothers with depression, the researchers looked at the effects on the babies. However, in order to have a better comparison than just the women with depression who took a placebo in the NUTRIMUM trial, they compared the babies from moms who took DEN in the clinical trial to a group of babies from healthy (not depressed) moms taking regular multivitamins or not supplementing at all and to a group of babies born to moms who were taking antidepressant medication during their pregnancy.


Prenatal Study (2024) NBAS cluster scales post-birth - Habituation, Orientation, Motor, Regulation of State, and Autonomic Stability.webp

Enhanced Neonatal Outcomes

Babies from moms who took DEN for depression during pregnancy were significantly better off than newborns from moms taking pharmaceutical antidepressants on six out of seven physiological and neurological measures (habituation to disturbances, orientation to sights and sounds, motor control, regulation of state, autonomic stability, and normal reflexes).

The “DEN babies” even outperformed babies from otherwise healthy, unmedicated moms on three of the seven measures (habituation to disturbances, motor control, and autonomic stability). 

Optimal Gestation and Birth

Micronutrient-exposed infants were also more likely to be carried to full term than infants from healthy, unmedicated mothers and mothers taking antidepressants. Babies carried to full term tend to experience better lifelong outcomes than those born pre-term. 

The micronutrients helped psychological functioning in moms and improved birth outcomes in babies. The micronutrients also appear to have mitigated some of the risks associated with antenatal depression and poorer infant outcomes. These are some of the benefits of higher dose and better balance of nutrients compared to typical over-the-counter antenatal nutritional supplements. See the study.

What Makes Daily Essential Nutrients Unique?

Our Daily Essential Nutrients formula is meticulously crafted to provide a broad spectrum of essential vitamins and minerals that are often lacking in modern diets. This comprehensive approach ensures that the body receives the nutrients it needs to function optimally, which in turn supports mental health and emotional well-being.


Key Characteristics of DEN Include:

  • All the known essential vitamins and minerals

  • A well-balanced formulation 

  • Proprietary chelation to increase mineral bioavailability
  • A high enough dose to supply the body’s true needs

Testimonials from Real Users

We have always believed in the power of our supplements, but hearing from our customers is what truly drives us. Here are a few testimonials from individuals who have experienced the benefits of Daily Essential Nutrients firsthand:

-Emily S. shared, "Since starting DEN, I’ve noticed a remarkable change in my mood. I feel more balanced and less anxious. It’s been a game-changer for me!"
-Mara T. mentioned, "I was skeptical at first, but after a few weeks on DEN, my depression symptoms started to lift. I can’t thank Hardy Nutritionals enough."

The Future of Mental Health Support

This study marks over 50 independent medical journal publications backing DEN as a safe and effective alternative for mental health, securing its place once again as the world’s most research-backed supplement for mood and mental health.

At Hardy Nutritionals, we are committed to advancing research in the field of nutritional psychiatry and providing high-quality, evidence-based products to support mental health. We believe that nutrition plays a crucial role in mental wellness, and we are dedicated to helping our customers achieve their best possible health.

The findings of this study affirm what many of our customers and their doctors already know: Hardy Nutritionals' Daily Essential Nutrients can significantly improve mental health. We are excited to continue our mission of improving mental health through nutrition and look forward to bringing you more innovative and effective solutions.

For more information on the NUTRIMUM study and to learn how Daily Essential Nutrients can benefit you, visit


Hardy Nutritionals® multivitamin-mineral products are powered by our proprietary NutraTek™ mineral delivery technology, which combines each mineral with specialized organic molecules—just like nature—to optimize absorption and distribution to body cells. Our flagship supplement, Daily Essential Nutrients, is widely considered to be the most research-backed micronutrient treatment.
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